日本語
The University of Electro-Communications 
Graduate School of Informatics and Engineering, School of Informatics and Engineering 
Department of Engineering Science, Cluster III (Fundamental Science and Engineering) 

顔写真 Associate Professor 
GENICHI SANPEI 

Year of birth:1960  
Tel.0424-43-5481  
Fax.0424-43-5501  
 
Personal website  

Career
東京大学理学部  助手  1989/06/16-1993/03/31 
東京大学大学院理学系研究科  助手  1993/04/01-1994/03/31 
電気通信大学電気通信学部  助手  1994/04/01-1999/11/24 
電気通信大学電気通信学部  講師  1999/11/25-2010/03/31 
電気通信大学大学院情報理工学研究科  講師  2010/04/01-2014/03/31 
電気通信大学大学院情報理工学研究科  准教授  2014/04/01-Present 

Academic background
福島県立安積高等学校  普通科  1979/03/31  Graduated 
The University of Tokyo  Faculty of Science  生物化学科  1984/03/31  Graduated 
The University of Tokyo  Graduate School, Division of Science  生物化学専攻  Master's program  1986/03/31  Completed 
The University of Tokyo  Graduate School, Division of Science  生物化学専攻  Doctoral program  1989/06/15  Program completed without degree 
The University of Tokyo  Graduate School, Division of Science  生物化学専攻  Doctoral program  1990/03/31  Completed 

Academic degrees
理学博士  The University of Tokyo  1990/03 

Classes responsible within the university
2017  Biochemistry and Engineering  Spring semester  Undergraduate, daytime  Subject in specialty 
2017  Bioscience and Technology Laboratory Ⅰ  Spring semester  Undergraduate, daytime  Subject in specialty 
2017  Bioscience and Technology Laboratory ⅠI  Fall semester  Undergraduate, daytime  Subject in specialty 
2017  Systems Biology  Fall semester  Undergraduate, daytime  Subject in specialty 
2017  Selected Topics in Genome Biology  Fall semester  Graduate, IE  Master's and doctoral programs  Subject in specialty 
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Current research areas
Molecular biology 
Genome biology 
Structural biochemistry 

Research keywords
Genome 
Organization 
Diversification 
Biosynthetic pathway 
X-ray crystallography 
Regulation of gene expression 
System's biology 
Metabolic system 

Current research subjects
X-ray crystallographic analysis of the purine nucleotide biosynthetic enzymes from various thermophilic bacteria with focusing on Thermus thermophilus.  X-ray crystallography purine nucleotide biosynthetic pathway thermophilic bacteria  2002-Present 
Regulation of gene expression in the purine nucleotide biosynthetic operons from Thermus thermophilus  gene expression purine biosythetic pathway  2002-Present 
Organization of purinc nucleotidc biosynthetic pathway  Organization purine nucleotide  1997-Present 
Organization and diversification of plasmid genomes  plasmid genome  1996-2012 

Published books
Book  基礎生化学実験  三瓶嚴一(分担執筆)  東京化学同人  107-129  1994/11 
Book  構造生物学 -ポストゲノム時代のタンパク質研究-  三瓶嚴一(分担執筆)  共立出版  227-234  2007/04 
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Published papers
Paper  Yes  Crystal structures of a subunit of the formylglycinamide ribonucleotide amidotransferase, PurS, from Thermus thermophilus, Sulfolobus tokodaii and Methanocaldococcus jannaschii  Joint  Yuzo Watanabe, Hisaaki Yanai, Mayumi Kanagawa, Sakiko Suzuki, Satoko Tamura, Kiyoshi Okada, Seiki Baba, Takashi Kumasaka, Yoshihiro Agari, Lirong Chen, Zheng-Qing Fu, John Chrzas, Bi-Cheng Wang, NorikoNakagawa, Akio Ebihara, Ryoji Masui, Seiki Kuramitsu, Shigeyuki Yokoyama, Gen-ichi Sampei and Gota Kawai  Acta Crystallogr Sect F Struct Biol Cryst Commun.  72, 627-635  2016/08/01 
Paper  Yes  Crystal structures and ligand binding of PurM proteins from Thermus thermophilus and Geobacillus kaustophilus  Joint  Mayumi Kanagawa, Seiki Baba, Yuzo Watanabe, Noriko Nakagawa, Akio Ebihara1, Seiki Kuramitsu, Shigeyuki Yokoyama, Gen-ichi Sampei and Gota Kawai  J Biochem.  159/ 3, 313-321  2016/02 
Paper  Yes  Structures and reaction mechanisms of the two related enzymes, PurN and PurU.  Joint  Gen-ichi Sampei, Mayumi Kanagawa, Seiki Baba, Toshiaki Shimasaki, Hiroyuki Taka, Shohei Mitsui, Shinji Fujiwara, Yuki Yanagida, Mayumi Kusano, Sakiko Suzuki, Kayoko Terao, Hiroya Kawai, Yoko Fukai, Noriko Nakagawa, Akio Ebihara, Seiki Kuramitsu, Shigeyuki Yokoyama and Gota Kawai  J Biochem.  154/ 6, 569-579  2013/12 
Paper  Yes  Structure of N-formylglycinamide ribonucleotide amidotransferase II (PurL) from Thermus thermophilus HB8  Joint  Sakiko Suzuki, Hisaaki Yanai, Mayumi Kanagawa, Satoko Tamura, Yuzo Watanabe, Kyotaro Fuse, Seiki Baba, Gen-ichi Sampei and Gota Kawai  Acta Crystallogr Sect F Struct Biol Cryst Commun.  68, 14-19  2012/01 
Paper  Yes  Crystal Structures of Glycinamide Ribonucleotide Synthetase, PurD, from Thermophilic Eubacteria.  Joint  Gen-ichi Sampei., Seiki Baba, Mayumi Kanagawa, Hsaaki Yanai, Takeshi Ishii, Hiroya Kawai, Yoko Fukai, Akio Ebihara , NorikoNakagawa, Gota Kawai  J Biochem.  148/ 4, 429-438  2010/10 
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Research presentations
Oral presentation for an academic conference  Sulfolobus tokodaii 由来PurQタンパク質の無細胞合成系による調製とグルタミナーゼ活性の確認  第87回日本生化学会大会  No  渡辺雄三, 三瓶嚴一, 河合剛太  2014/10 
Oral presentation for an academic conference  Crystal structures of PurM proteins from thermophiles  第87回日本生化学会大会  No  Mayumi Kanazawa, Seiki Baba, Yuzo Watanabe, Gen-ichi Sampei, Gota Kawai  2014/10 
Oral presentation for an academic conference  Origin and evolution of the protein structures in the purine biosynthetic pathway : Reaction mechanism of N5-CAIR synthetase (PurK) and evolutionary relationships with related enzymes  第87回日本生化学会大会  No  Gen-ichi Sampei and Gota Kawai  2014/10 
Oral presentation for an academic conference  Interaction analysis between PurF and PurD from Thermus thermophilus HB8  Whole-organism science society Meeting of structural-biological whole cell project  No  Hironori Ishii, Gota Kawai and Gen-ichi Sampei  2014/09 
Oral presentation for an academic conference  Reaction mechanism of glutamine amidotranferases in the purine biosynthesis  Whole-organism science society Meeting of structural-biological whole cell project  No  Yuzo Watanabe, Gen-ichi Sampei and Gota Kawai  2014/09 
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Intellectual property rights
Patent  新規プラスミド及び当該プラスミドを含むシャトルベクター  特願2002-309721  2002/10/24  特開2004-141065  2004/05/20  Published 
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Researcher accepted
Domestic  Post-doctoral researcher  日本  プリン・プリミジンヌクレオチド生合成系酵素の立体構造解析  2006-2007 
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Past records of joint or funded research
乳酸菌ゲノムの解析  2001-2002  Commissioned research  Research commissioned by a company 
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Memberships of academic societies
日本分子生物学会  1984-Present 
日本結晶学会  2001-Present 
モデル生物丸ごと一匹学会  2011/08-Present 
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Involvement in conference and research meetings
電気通信大学生命科学シンポジウム 『生命システム原材料の起源と進化:生化学的禁制律』  オーガナイザー  2013/03/09 
理研・千葉工業大学共催シンポジウム「生命システム原材料の起源と進化:生体分子は如何にして作られたか?」  企画・運営委員  2011/11/26 
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Committee or council involvement
モデル生物丸ごと一匹学会  理事  2011/08-Present 
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Social activities
Participation in community support activities, etc.  杉並区立宮前公園竹林の集い  2016/04/23-Present  公園内に自生している竹林の保全のために間伐を行う。および,地域の子供たちに竹の加工の仕方を指導する。 
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Committee activity in the University
広報委員会  委員  2017/04-Present 
情報基盤システム仕様策定委員会  委員  2017/01-2017/06 
学部教育委員会  委員  2015/02-2017/03 
教職課程部会  委員  2013/04-2015/03 
安全・環境保全室薬品管理部門  部門員  2011/02-Present 
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