日本語
The University of Electro-Communications 
Graduate School of Informatics and Engineering, School of Informatics and Engineering 
Department of Engineering Science, Cluster III (Fundamental Science and Engineering) 

顔写真 Associate Professor 
HIDEKI SHIRAKAWA 

Year of birth:1965  
Personal website  

Career
Tokyo Women's Medical University  Instructor  1991/04/01-2002/06/30 
Tokyo Women's Medical University  Assistant Professor  2002/07/01-2005/09/30 
The University of Electro-Communications  Associate Professor  2005/10/01-2007/03/31 
電気通信大学  准教授  2007/04/01-Present 

Academic background
The University of Tokyo  Graduate School, Division of Science  動物学  Master's program  1991  Completed 
University of Tsukuba  Second Cluster of College  生物学類  1989  Graduated 
私立武蔵高等学校  1984/03/31  Graduated 

Academic degrees
理学修士  東京大学 
博士(医学)  東京女子医科大学 

Classes responsible within the university
2017  細胞生物工学  Spring semester  Undergraduate, daytime  Subject in specialty 
2017  生物学  Spring semester  Undergraduate, mainly nighttime  Liberal arts 
2017  分子細胞生物学基礎  Spring semester  Graduate, IE  Master's program  Subject in specialty 
2017  基盤理工学専攻基礎  Spring semester  Graduate, IE  Master's program  Subject in specialty 
2017  生体計測工学  Fall semester  Undergraduate, daytime  Subject in specialty 
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Classes responsible in other universities
2017  生体システムと制御機構  東京女子医科大学 
2017  細胞の基本機能  東京女子医科大学 
2016  生体システムと制御機構  東京女子医科大学 
2016  細胞機能と機能物質  東京女子医科大学 
2015  生体システムと制御機構  東京女子医科大学 
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Current research areas
Biophysics 
Cell biology 
General physiology 

Current research subjects
Regulatory mechanism of intracellular calcium dynamics  calcium ion, calcium imaging, inositol trisphosphate  1991-Present 
Development of multi-spectral imaging system  fluorescence, spectral decomposition  2002-Present 

Published books
Book  細胞内カルシウム実験プロトコール  白川英樹、宮崎俊一  羊土社  1996 
Book  電子顕微鏡基礎技術と応用~物質のナノ局在解析~  白川英樹、宮崎俊一  学際企画  1994 
Book  Biology of Germ Lines in Animals and Man  Miyazaki, S., Nakada, K., and Shirakawa, H.  Japan Scientific Societies Press  1993 
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Published papers
Paper  Yes  Ca2+ signaling in mammalian eggs at ferilization  Joint  Shirakawa, H., Kikuchi, T., Ito, M.  Current Topics in Medicinal Chemistry  16/ 24, 2664-2676  2016 
Paper  Yes  Ca2+ influx-dependent refilling of intracellular stores determines the frequency of Ca2+ oscillations in fertilized mouse eggs  Takahashi, T., Kidokoro, Y., Kikuchi, T., Shirakawa, H.  Biochemical Biophysical Research Communications  430, 60-65  2013 
Paper  Yes  Measurement of intracellular IP3 during Ca2+ oscillations in mouse eggs with GFP-based FRET probe  Shirakawa, H., Ito, M., Sato, M., Umezawa, Y., and Miyazaki, S.  Biochemical Biophysical Research Communications  345, 781-788  2006 
Paper  Yes  The role of EF-hand domains and C2 domain in regulation of enzymatic activity of phospholipase C-zeta  Kouchi, Z., Shikano, T., Nakamura, Y., Shirakawa, H., Fukami, K., and Miyazaki, S.  Journal of Biological Chemistry  280, 21015-21021  2005 
Paper  Yes  Nuclear translocation of phospholipase C-zeta, and egg-activating factor, during early embryonic development  Sone, Y., Ito, M., Shirakawa, H., Shikano, T., Takeuchi, H., Kinoshita, K., and Miyazaki, S.  Biochemical Biophysical Research Communications  330, 690-694  2005 
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Research presentations
Oral presentation for an academic conference  Role of luminal Ca2+ binding proteins in the pattern formation of Ca2+ oscillations in mammalian eggs  第94回日本生理学会  67/ Suppl 1  No  Murata, T., Kikuchi, T., Shirakawa, H.  2017/03/30 
Oral presentation for an academic conference  Calcium oscillation-dependent dynamics of cortical actin filaments in mouse eggs  The 22nd International Congress of Zoology  Abstract  No  Yoshida, T., and Shirakawa, H.  2016/11/18 
Oral presentation for an academic conference  Functional requirements of interdomain interactions for the enzymatic activity of PLCzeta  The 22nd International Congress of Zoology  Abstract  No  Yamada, N., Tsuda, T., Shirakawa, H.  2016/11/18 
Oral presentation for an academic conference  Measurement and analysis of changes in the ER Ca2+ concentrations during Ca2+ oscillations in mouse eggs.  Oocyte Maturation and Fertilization Meeting IV  Abstract  No  Kikuchi, T., Murata, T., Shirakawa, H.  2015/06/17 
Oral presentation for an academic conference  Mechanism for the generation of fast and slow Ca2+ oscillations in mouse eggs.  Oocyte Maturation and Fertilization Meeting IV  Abstract  No  Shirakawa, H., Kikuchi, T., Yamada, Y., Tsuda, T.  2015/06/17 
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Memberships of academic societies
Biophysical Society(アメリカ) 
日本生物物理学会 
日本発生生物学会 
日本生理学会 
日本動物学会  2007/05-Present 
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Committee or council involvement
日本生理学会  評議員  2000-Present 
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Committee activity in the University
遺伝子組換え実験安全委員会  委員  2013/04-Present 
国際科目企画・運営小委員会  委員長  2012/11-2016/03 
動物実験委員会  委員  2009/05-Present 
ヒトを対象とする実験に関する倫理委員会  委員  2006/09-Present 
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