日本語
The University of Electro-Communications 
Graduate School of Informatics and Engineering, School of Informatics and Engineering 
"Department of Engineering Science, Cluster III (Fundamental Science and Engineering)" 

顔写真 Associate Professor 
HIDEKI SHIRAKAWA 

Year of birth:1965  
Personal website  

Career
Tokyo Women's Medical University  Instructor  1991/04/01-2002/06/30 
Tokyo Women's Medical University  Assistant Professor  2002/07/01-2005/09/30 
The University of Electro-Communications  Associate Professor  2005/10/01-2007/03/31 
電気通信大学 電気通信学部  准教授  2007/04/01-2010/03/31 
The University of Electro-Communications  准教授  2010/04/01-Present 

Academic background
私立武蔵高等学校  1984/03/31  Graduated 
University of Tsukuba  Second Cluster of College  生物学類  1989/03/31  Graduated 
The University of Tokyo  Graduate School, Division of Science  動物学  Master's program  1991/03/31  Completed 

Academic degrees
理学修士  東京大学 
博士(医学)  東京女子医科大学 

Classes responsible within the university
2019  細胞生物工学  Spring semester  Undergraduate, daytime 
2019  分子細胞生物学基礎  Spring semester  Graduate, IE  Master's program 
2019  生体計測工学  Spring semester  Undergraduate, daytime 
2019  生体機能システム演習第二  Fall semester  Undergraduate, daytime 
2019  現代化学  Fall semester  Undergraduate, daytime 
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Classes responsible in other universities
2005  細胞機能と機能物質  東京女子医科大学 
2005  脳神経系I  東京女子医科大学 
2006  細胞機能と機能物質  東京女子医科大学 
2006  脳神経系I  東京女子医科大学 
2007  細胞機能と機能物質  東京女子医科大学 
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Current research areas
Biophysics 
Cell biology 
General physiology 

Current research subjects
Regulatory mechanism of intracellular calcium dynamics  calcium ion, calcium imaging, inositol trisphosphate  1991-Present 
Development of multi-spectral imaging system  fluorescence, spectral decomposition  2002-Present 
Development of fluorescent probes for bio-imaging of living cells  fluorescent protein, bioimaging  2006-Present 
Regulation of intracellular signaling molecules by optogenetical methods  optogenetics  2013-Present 

Published books
Book  細胞内カルシウム実験プロトコール  白川英樹、宮崎俊一  羊土社  1996 
Book  電子顕微鏡基礎技術と応用~物質のナノ局在解析~  白川英樹、宮崎俊一  学際企画  1994 
Book  Biology of Germ Lines in Animals and Man  Miyazaki, S., Nakada, K., and Shirakawa, H.  Japan Scientific Societies Press  1993 
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Published papers
Paper  Yes  Dual-FRET imaging of IP3 and Ca2+ revealed Ca2+-induced IP3 production maintains long lasting Ca2+ oscillations in fertilized mouse eggs  Joint  Matsu-ura, T., Shirakawa, H., Suzuki, K.G.N., Miyamoto, A., Sugiura, K., Michikawa, T., Kusumi, A., Mikoshiba, K.  Scientific Reports  9/ 1, 4829-  2019/03/18 
Paper  Yes  Ca2+ signaling in mammalian eggs at ferilization  Joint  Shirakawa, H., Kikuchi, T., Ito, M.  Current Topics in Medicinal Chemistry  16/ 24, 2664-2676  2016 
Paper  Yes  Ca2+ influx-dependent refilling of intracellular stores determines the frequency of Ca2+ oscillations in fertilized mouse eggs  Joint  Takahashi, T., Kidokoro, Y., Kikuchi, T., Shirakawa, H.  Biochemical Biophysical Research Communications  430, 60-65  2013 
Paper  Yes  Measurement of intracellular IP3 during Ca2+ oscillations in mouse eggs with GFP-based FRET probe  Joint  Shirakawa, H., Ito, M., Sato, M., Umezawa, Y., and Miyazaki, S.  Biochemical Biophysical Research Communications  345, 781-788  2006 
Paper  Yes  The role of EF-hand domains and C2 domain in regulation of enzymatic activity of phospholipase C-zeta  Kouchi, Z., Shikano, T., Nakamura, Y., Shirakawa, H., Fukami, K., and Miyazaki, S.  Journal of Biological Chemistry  280, 21015-21021  2005 
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Research presentations
Oral presentation for an academic conference  Improvement of genetically encoded probe to measure Ca2+ dynamics in subcellular compartments  The 9th Federation of the Asian and Oceanian Physiological Societies Congress  2P-437  No  Murooka, N., Kikuchi, T., Shirakawa, H.  2019/03/30 
Oral presentation for an academic conference  Calcium-dependent regulation of cortical actin filaments in mouse eggs  The 9th Federation of the Asian and Oceanian Physiological Societies Congress  1P-506  No  Arakawa, S., Yoshida, T., Shirakawa, H.  2019/03/29 
Oral presentation for an academic conference  Dynamic reconstruction of Golgi apparatus during mammalian oocyte maturation  第95回日本生理学会  68/ Suppl 1  No  Iguchi, T., Shirakawa, H.  2018/03/28 
Oral presentation for an academic conference  Manipulating intracellular concentration of inositol trisphosphate by photoactivatable enzymes  第95回日本生理学会  68/ Suppl 1  No  Enokida, Y., Yamada, N., Yanagisawa, R., Shirakawa, H.  2018/03/28 
Oral presentation for an academic conference  Role of luminal Ca2+ binding proteins in the pattern formation of Ca2+ oscillations in mammalian eggs  第94回日本生理学会  67/ Suppl 1  No  Murata, T., Kikuchi, T., Shirakawa, H.  2017/03/30 
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Memberships of academic societies
日本動物学会  2007/05-Present 
Biophysical Society(アメリカ)  2004/10/01-Present 
日本生物物理学会  1994-Present 
日本発生生物学会  1993-Present 
日本生理学会  1992-Present 
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Committee or council involvement
日本生理学会  評議員  2000-Present 
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Committee activity in the University
遺伝子組換え実験安全委員会  委員  2013/04-Present 
動物実験委員会  委員  2009/05-Present 
ヒトを対象とする実験に関する倫理委員会  委員  2006/09-Present 
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